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2.5 mg once weekly for 4 weeks (this is a titration dose to help the body adjust and minimize gastrointestinal side effects)
This is why sublingual nitroglycerin works within minutes for angina, and why sublingual peptide delivery has attracted research interest
The wearing-off pattern is most pronounced during weeks one through four, before steady state is achieved
Expanded clinical uses could help treat metabolic problems and chronic kidney disease
