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Veterans cohort, for instance, sodium-glucose cotransporter 2 (SGLT2) inhibitors were found to be associated with a higher rate of peripheral artery disease-related surgical events than DPP-4 inhibitors (11.2 vs

However, clinical research increasingly recognized that patients with metabolic diseases frequently experience clusters of systemic complications, including heart failure (HF), chronic kidney disease (CKD), and fatty liver disease, that single-target drugs historically failed to address comprehensively

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doi: 10.1097/TXD.0000000000000971

Mantovani A, Petracca G, Beatrice G, Csermely A, Lonardo A, Targher G (2021) Glucagon-like peptide-1 receptor agonists for treatment of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: an updated meta-analysis of randomized controlled trials