glp-1 and cancer GLP-1s tied to lower risk for 10 types of compared with insulin in type 2 diabetes Glucagon-like peptide 1 receptor agonists

Coughlins closing line on the GLP-1 category captured the strategic logic: Were not interested in kind of me-too entries. With Entresto facing generic erosion and Leqvio soon confronting oral PCSK9 competition from Mercks Enlicitide, Novartis is staking its cardiovascular future on mechanisms that sit adjacent to not inside the metabolic pathway that everyone else is chasing

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Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Insulin Glargine as Add-on to Metformin (With or Without Sulfonylureas) in Insulin-Naive Patients With Type 2 Diabetes (SUSTAIN 4): A Randomised, Open-Label, Parallel-Group, Multicentre, Multinational, Phase 3a Trial