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Additional molecular regulatory mechanisms The inhibitory effect of GLP-1RAs on NF-B has been shown to suppress the proliferation of pancreatic cancer cells [66]

[DOI] [PubMed] [Google Scholar] 36.Leptin resistance and diet-induced obesity: central and peripheral actions of leptin
doi: 10.1111/dom.14725 23 MollHFreyEGerberPGeidlBKaufmannMBraunJet al

Sitagliptin treatment at the time of hospitalization was associated with reduced mortality in patients with type 2 diabetes and COVID-19: a multicenter, case-control, retrospective, observational study

We then investigated the association between initiation of a GLP-1 receptor agonist and the composite outcome in patients with specific categories of pre-existing SUDs, including disorders related to alcohol, cocaine, and opioids, and other SUD, given their strong relevance to clinically significant SUD associated adverse outcomes
