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DOI: 10.1210/en.2013-1934 [Google Scholar] Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, et al

However, recent evidence that glucagon increases energy expenditure independently of BAT activation in humans [64] indicates that alternative mechanisms such as futile substrate cycling [65] may underlie glucagons thermogenic properties