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CKD = Chronic Kidney Disease

In -cell-derived IN-R1-G9 cells, insulin inhibits glucagon release via activation of phosphatidylinositol 3-kinase (PI3K)
With NO bioavailability maintained, endothelium-mediated vasorelaxation was preserved and vascular remodeling and fibrosis were prevented (Helmstadter et al

Benjamini-Hochberg adjusted P ( d - i )
