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No, weight-loss medications such as semaglutide and tirzepatide are not recommended for use during pregnancy or while breastfeeding

However, Type 2 diabetes also carries a high risk for long-term complications affecting vision, cardiovascular health, kidneys, and nerves all of which can be disqualifying for pilots
In one study, GLP-1s were found to act directly on skin cells, potentially worsening facial thinning beyond fat loss alone
GLP-1 receptor agonists remain blockbuster drugs for weight management for people with overweight or obesity

Gut microbial metabolites in obesity, NAFLD and T2DM
