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These mixed results reflected the broader challenge of the oral race: convenience alone was no longer enough to guarantee success oral candidates would have to demonstrate durability, safety, and cardiometabolic value comparable to injectables

Similarly, the SELECT cardiovascular outcome trial, which followed over 17,000 patients with obesity but without diabetes for more than three years, found no significant elevation in cancer rates among semaglutide users

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Your healthcare provider will help you determine what diet, exercise, and medications are best for you

The way that FDA approval works is that you get a label for a drug if you can prove with the right degree of statistical significance that the benefits outweigh the risks and that you are better than current alternatives by some measurable amount