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Starting at a low dose gives you the best chance of a smooth adjustment

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The authors note the meta-analysis did not include studies of lifestyle interventions and bariatric surgery, reducing the degree to which different weight loss approaches could be compared within the context of the study

Staying hydrated with Hydrate or Die can also help manage the feelings of nausea associated with dehydration

Pinch a fold of skin at the injection site with your non-dominant hand Hold the syringe at a 90-degree angle to the skin surface Insert the needle fully into the pinched skin fold in one smooth motion Release the skin pinch Push the plunger slowly and steadily until all medication is delivered Wait 5 to 10 seconds before removing the needle (this prevents medication from leaking back out) Remove the needle and apply gentle pressure with a clean cotton ball or gauze if needed Dispose of the syringe in a sharps container immediately Do not rub the injection site