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Integrating them into obesity management requires ongoing education and training to ensure that clinicians are prepared to prescribe and monitor these therapies and align them with nutritional counselling and behavioural support within an evidence-based framework [26, 67, 95]

Patients should contact their GP or prescribing clinician if headaches are severe, persistent beyond the first few weeks of treatment, or progressively worsening despite conservative management measures

A data sharing statement provided by the authors is available with the full text of this article at NEJM.org

Its hard to say because coverage varies considerably from plan to plan

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