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Common side effects at any dose include nausea, vomiting, constipation, and mild diarrhea, typically diminishing over 4 to 8 weeks as your body adjusts

[12] Patients with Hashimoto's disease often have detectable thyroid autoantibodies in their blood, particularly anti-thyroid peroxidase (anti-TPO) antibodies and, less commonly, anti-thyroglobulin antibodies

That cardiovascular indication is a clinically and commercially powerful differentiator

Clinical evidence supporting weight loss Clinical trials show the effectiveness of semaglutide for weight loss

Patients and healthcare professionals are encouraged to report suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)