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These effects are generally mild to moderate and often decrease over time
GLP-1 use is safe and effective with many pre-existing conditions with the exception of the following: Currently pregnant Currently breastfeeding Currently being treated for cancer Active eating disorder Active gallbladder disease Active substance abuse or dependency Type 1 diabetes Bariatric surgery (within the past 18 months) Pancreatitis within the past 6 months, or a history of pancreatiitis caused by taking a GLP-1 Personal or family history of medullary thyroid cancer or MEN syndrome Personal history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Popular FAQ Zepbound vs Mounjaro: Comparison Guide for Weight Loss and Diabetes Treatment Zepbound and Mounjaro contain tirzepatide and are made by Eli Lilly
The treatment regimen estimand assessed effects regardless of treatment adherence in the intention-to-treat population
DOI: 10.1016/S0140-6736(23)01200-X [16] Wadden, T.A., Chao, A.M., Machineni, S., et al
