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[14] This may be clinically relevant in patients with pre-existing cardiovascular conditions and should be monitored

The main concerns focused on two specific cancer types: Thyroid cancer: Animal studies showed that very high doses of GLP-1 medications caused thyroid tumours in rodents

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Reassess how much and how often you drink

When combined with GLP-1 agonism, glucagon receptor activation increases energy expenditure through thermogenesis, enhances fat oxidation and breakdown, improves metabolic rate in ways that counteract the metabolic slowdown typically accompanying weight loss, and may provide additional central appetite regulation
