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Data on patient-reported outcomes for individual GLP-1RAs indicate high treatment satisfaction rates with the long-acting agents (Table 3) [69,70,71,72,73,74], while dulaglutide was associated with higher adherence and persistence rates than exenatide QW and liraglutide [75]

First, novel analogues with enhanced central penetration or receptor selectivity should be prioritized

The glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are attractive options for the treatment of T2D because they effectively lower A1C and weight while having a low risk of hypoglycemia

GLP-1 agonists primarily aid in weight loss and cardiovascular protection, while SGLT2 inhibitors provide strong kidney and heart failure benefits

Breaking News, Collaborations & Alliances Novo Nordisk, Ascendis Ink $285M GLP-1 Pact To leverage Ascendis TransCon technology platform for once-monthly GLP-1 receptor agonist candidate