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Meanwhile, Liraglutide treatment significantly reduces the diabetes-induced increases in glomerular fibronectin, collagen type IV, and -smooth muscle actin and decreases in glomerular Wnt/-catenin signaling proteins
In our study, liraglutide prevented the TGF-1 + IL-1-induced augmentation of mitochondrial respiration in fibroblasts, indicating that activating GLP-1R could maintain mitochondrial homeostasis under inflammatory stress
Dig Dis Sci 58:301723
Therapeutic Advances in Chronic Disease
Berenbaum, F
