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It acts on GLP-1, GIP and glucagon receptors and has attracted strong interest in metabolic research, particularly in models of appetite regulation, body-weight change, glycaemic control and energy balance

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Retatrutide primarily operates on a systemic, hormonal level, influencing appetite, satiety, and glucose regulation through its triple agonism of GIP, GLP-1, and glucagon receptors

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Submission for the use of the drug to treat type 2 diabetes is expected next year.

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& Condorelli, F

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