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Retatrutide is a triple agonist, targeting three receptors: GIP, GLP-1, and glucagon

Mechanism underlying the weight loss and complications of roux-en-y gastric bypass
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Gorgojo-Martnez JJ, Mezquita-Raya P, Carretero-Gmez J, et al.

2018 Jun 16;392(10157):1519-1529