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Back Deacon, DF, Johnsen, AH, Holst, JJ (March 1995) 'Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo', Journal Clinical Endocrinology Metabolism , 80/3, 952-7

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To solve this issue, in this study, we devised an endosomal co-localization study to detect the presence of active GLP-1R in pancreatic islet cells

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The first is the MAPK/ERK pathway and the PI3K/AKT pathways, which can modulate events such as activation of calcium channels, increased protein synthesis, mitochondrial biogenesis, inhibition of apoptosis, inflammation, and protein aggregation, leading to improved cell survival [74,80]

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Relationship between body weight change and glycemic control with tirzepatide treatment in people with type 2 diabetes (abstract)

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