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Glucose-Dependent Insulinotropic Polypeptide in Incretin Physiology: Role in Health and Disease

While Ozempic shares the same active ingredient as some weight loss medications, its primary indication is diabetes management

However, application of APLs in MS may be a double-edged sword

These include the ghrelin-LEAP2 system and the activity of the GHSR, including its constitutive activity

[5] [8] Animal studies have shown thyroid C-cell tumours (medullary thyroid carcinoma) with some GLP-1 receptor agonists, but there is no confirmed link in humans and this is not a formal contraindication in UK prescribing information