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Ann Transl Med (2021) 9(14):1156
As this market expands from consumer wellness tools to regulated medical devices, developers face complex challenges in integration, compliance, data security, and scalability

Intestinal Fc receptor-targeted polymeric micelles increased the oral exposure of semaglutide 6-fold in type 2 diabetic mice while preserving its glucose-lowering efficacy [194]

Therefore, GLP-1RAs that mimic the function of native GLP-1 but with improved pharmacokinetics are highly desirable as drug candidates for the management of T2DM (Prajapati et al., 2024)
Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial