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Eloralintide's tolerability profile may differ from other amylin receptor agonists because of its unique biochemical structure or receptor selectivity

Common issues include nausea, diarrhea, constipation, and fatigue

Like other peptide therapeutics, anti-drug antibodies have been observed in clinical studies, though their clinical significance continues to be evaluated

However, retatrutide is not yet FDA approved and availability is limited to clinical trials and research settings

This is actually part of the therapeutic mechanism, since delayed gastric emptying contributes to appetite suppression and reduced caloric intake