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One study saw a fairly modest bump, something like the low 300s up to the high 360s, while the trials in heavier men with metabolic low T show more

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The choice depends on individual circumstances, thyroid stability, and clinical suitability

It might be electrolyte concentration

Other Emerging Therapeutic Targets Amylin Mimetics Amylin is a neuroendocrine peptide co-secreted by pancreatic -cells postprandially with insulin and acts to inhibit glucagon secretion, reduce gastric emptying and centrally induce satiety [76]