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Available from: Blevins T, Pullman J, Malloy J, et al
Weight Loss Pill Could Be a New Choice for People With Obesity The pill appears to be as safe and well-tolerated as injected GLP-1 drugs, Lilly said
It turned out she was right
Wegovy Dig deeper: Zepbound and Wegovy are both GLP-1 drugs approved for weight loss, but Zepbound targets two hormones, GIP and GLP-1, while Wegovy only targets GLP-1
Mechanistically, GLP-1R activation appears to downregulate TNF- production via 1-adrenergic, -opioid, and -opioid receptor pathways (Wong et al., 2024)
