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Lifestyle Adjustments Regular Exercise: Activities like walking, running, or strength training can help burn calories and improve insulin sensitivity

SURMOUNT Trial Data, What Researchers Are Working From The pivotal SURMOUNT-1 trial (Jastreboff et al., NEJM 2022, NCT04184622) enrolled 2,539 adults with obesity (no type 2 diabetes) over 72 weeks

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After Week 48, participants in treatment groups 1 (placebo) and 2 (bimagrumab 10 mg/kg) switched to bimagrumab 30 mg/kg, while all other groups continued their original treatments without the placebo infusions during the 24-week open-label extension period

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