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Initiating estrogen therapy earlier in the menopausal transition, typically within 10 years of the final menstrual period and before age 60, is associated with a more favorable cardiovascular profile [26]

Perhaps more impressively, 89-93% of participants achieved less than 5% liver fat content, which is the threshold for being considered free of fatty liver disease

The update also reflects a broader shift in how medicines are being distributed, recognising that patients increasingly expect and benefit from direct-to-patient models, particularly for treatments relating to sensitive conditions such as obesity

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