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Description
eNAMPT actions through nucleus accumbens NAD+/SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress

Ghorpade DS, Ozcan L, Zheng Z, et al

Published clinical trials evaluating investigational retatrutide have reported gastrointestinal adverse events [1]

J Comp Neurol 271: 519532, 1988

In published phase-2 literature, retatrutide has been studied for its effects on body weight and metabolic markers, with the triple-receptor mechanism investigated as a way to pair appetite signalling with increased energy expenditure
