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Concerns have been expressed regarding the effects of these drugs on pancreatic and thyroid tissue, since animal studies and analyses of drug databases indicate an association of GLP-1 receptor agonists with pancreatitis, pancreatic cancer, and thyroid cancer

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Metabolic syndrome -basically heart disease, diabetes and their related conditions- are the top causes of death in the US and top costs to our health care system

They have also created a noisy market of med spas, online prescribing mills, influencer claims, compounded medication confusion, and patients wondering what is medically real