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Key results (Phase 3): In a 68-week Phase 3a trial published in The New England Journal of Medicine , cagrilintidesemaglutide (CagriSema) produced large mean weight loss (reported as ~22.7% at 68 weeks in the main efficacy analysis)

Ozempic is FDA-approved to help with blood sugar management in people with diabetes, while Wegovy is approved for weight loss in people who are overweight or struggle with obesity
Gastroenterology 122:531544 Drucker DJ, Yusta B, Boushey RP et al (1999) Human [Gly2]GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis
Association between ultra-processed food consumption and mortality among U.S

The authors compared it to insulin: both hormones show an initial surge in hormone levels followed by resistance to the effects of the hormone that outstrips your bodys ability to make more