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Consequently, optimizing the management in KTRs with DM is of paramount importance to improve long term outcomes

Semaglutide and tirzepatide prescribing information and safety labeling

There are several reasons to explain this limited beneficial effect on HbA1c (and also on body weight)

Note that the percentage range (abscissa) varies

In the LEADER study, acute gallbladder or biliary tract disease increased when liraglutide was used, and a recent meta-analysis reported an increased risk of cholelithiasis
