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The choice for K = 10 was based on a combination of minimizing cross-validation errors for admixture analysis, as well as minimizing the Frobenius distance of each ADMIXTURE matrix K with the matrix outputted by Genetic Relationship and Fingerprinting
The glucagon component is the mechanistic differentiator and is hypothesized to drive the higher weight loss observed in earlier-phase studies
Non-arteritic anterior ischemic optic neuropathy (NAION) is a condition that affects the optic nerve
