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Across premenopausal, perimenopausal, and postmenopausal women, tirzepatide produced similar reductions in body weight, waist circumference, and central adiposity

Patients often experience faster results with tirzepatide, though side effects like nausea may occur during dose escalation

GLP-1 Pharmacology Glucagon-like peptide 1 agonists simulate the action of incretin, which is a hormone produced by the small intestines, that bind to the GLP-1 receptor

In the age of genetically-modified autologous T cells used in 2nd line refractory multiple myeloma, the idea that a single peptide could treat almost everyone that was obese seemed incomprehensible, a Mad Men-esque throwback to the 90s with Prozac, Lipitor, and Viagra