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Description
GLP-1 directly activates anorexigenic POMC and CART neurons and indirectly inhibits, via GABAergic transmission, orexigenic NPY and AgRP neurons [39]

This slow escalation minimizes gastrointestinal side effects and gives your body time to adjust

GLP-1 medications may cause uncomfortable side effects and increase the risk of gastrointestinal conditions

The incidence of headaches does not appear to increase with higher doses, though individual responses vary significantly

Many insurance companies will not cover the costs of these medications, especially for weight loss
