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Por otro lado, los frmacos de accin prolongada, permiten un mayor control de la glucemia basal, como la exenatida de liberacin prolongada, liraglutida, dulaglutida, albiglutida y por ltimo semaglutida, aprobada recientemente por la FDA 56 .Adems, se ha demostrado que los GLP1-RA disminuyen el riesgo de eventos cardiovasculares al influir positivamente en factores de riesgo como obesidad, presin arterial y perfil lipdico 15

Initially, a total of 559 articles were retrieved (PubMed n = 160, EMBASE n = 399)

They work by encouraging your body to release more insulin when you eat

The addition of glucagon receptor agonism introduces a third axis: increased energy expenditure, enhanced hepatic fat oxidation, and PCSK9-mediated reduction in LDL cholesterol

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