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Additionally, the expression of genes involved in GLP-1 biosynthesis was increased (proglucagon and prohormone convertase 3) 5

The findings were published in JAMA Network Open on March 31, indicating that gastrointestinal problems, including stomach paralysis and bowel obstruction, are the most common complaints by those taking diabetes and weight loss drugs like Ozempic, Mounjaro and Wegovy

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Its benefits largely depend on conversion into paraxanthine, while many of its drawbacks stem from theobromine and theophylline

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