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When the benefit outweighs the side effect, and when it might not For most patients, the metabolic benefits of GLP-1 therapy, including improved cardiovascular risk factors, better insulin sensitivity, reduced visceral fat, and meaningful weight loss, far outweigh a temporary or modest change in libido

Contact your GP surgery or NHS 111 for advice if you're uncertain whether symptoms represent normal Ozempic side effects or require assessment

Practice-changing articles that you need to know: semaglutide for weight loss

The risk for acute kidney injury in older adults is higher because they tend to have other comorbidities, such as hypertension and chronic kidney disease. Another concern is that rapid weight loss is often accompanied by a loss of muscle mass

However, no direct head-to-head trials comparing these agents for liver fat reduction have been conducted, so definitive comparative conclusions cannot yet be drawn