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Mediators Inflamm 2016:3094642 Kristensen SL, Rrth R, Jhund PS, Docherty KF, Sattar N, Preiss D, Kber L, Petrie MC, McMurray JJV (2019) Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials

Prepregnancy obesity and primary cesareans among otherwise low-risk mothers in 38 U.S

All individuals prescribed GLP-1 receptor agonists should also receive intensive, multicomponent behavioral interventionsincluding a nutrient-dense, reduced-calorie diet

These provide fibre and nutrients with minimal fat and moderate calories

Concerns specific to older patients include a higher risk of muscle loss during weight loss (sarcopenia), potential impact on bone density, a greater need for adequate protein intake and regular resistance training, and the possibility of more pronounced side effects, particularly nausea and dehydration