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For example, it includes making food cues more powerful in encouraging overeating, a phenomenon known as incentive sensitization (being extra sensitive to rewards)

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In the placebo condition, participants with obesity showed an imbalance common in overeating: their brain's reward areas lit up when the cue signaled the impending milkshake, indicating heightened craving or wanting, but their neural response during the actual tasting was blunted, indicating reduced liking

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Summary Alli interrupts digestion of dietary fats and blocks about 30% of fat from being absorbed