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The patients who will do best on these medications over the long term are those who use them within a framework that protects lean mass, supports metabolic health, and addresses the behavioural and physiological underpinnings of weight regain

[DOI] [PMC free article] [PubMed] [Google Scholar] 82
Trials are underway to explore their broader impactincluding on Alzheimers and inflammation

The results, which appear March 18 in BMJ Medicine, show that the consequences of stopping GLP-1 drugs go beyond weight regain, extending to increased cardiovascular risk, and underscore the importance of continuous treatment for sustained heart protection
