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Notably, no signal for ION was detected with tirzepatide, a dual GLP-1/GIP receptor agonist used for diabetes and obesity, and comparator drugs such as metformin and insulin also showed no significant associations

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Ozempic Ozempic is the brand name for the most common drug that uses the active ingredient semaglutide, which is predominately used to help manage diabetes

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Circulation Changes GLP-1s may alter blood flow to delicate areas like the retina or optic nerve