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Working solutions of GEP44, GEP12, Ex-4, or vehicle control were administered by subcutaneous injection once daily at the start of the dark cycle using a 1 cc 29G insulin syringe

Pharmacol Rep 2010;62:956-65.ArticlePubMed 98

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In addition, diet and exercise changes help to maintain weight loss long-term

It also reinforces a point I raised previously: that the clinical conversation at the point of prescribing needs to account for the individual patients baseline muscle mass and age-related risk profile, not simply their weight and BMI
