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Description
This loss is not merely a cosmetic inconvenience
In another Phase 2 trial published in the journal The Lancet in August 2023, patients taking the pill had an average 2.1% reduction in their A1C, a measure of long-term blood sugar, after 26 weeks

Oxyntomodulin and Glicentin May predict the effect of bariatric surgery on food preferences and weight loss
Molecular Nutrition & Food Research , 65(22), e2100071
From this, we can conclude that berberine mainly affects the number and function of cell to treat T2DM
