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However, whether peripherally injected GLP-1 actually makes it into the human brain, as suggested by some animal studies, is still a matter of debate
The direct recording of afferent renal nerve activity (ARNA) with intrapelvic injection of GLP-1 and total renal sympathetic nerve activity (RSNA) with intravenous infusion of GLP-1 were performed
In comparison with exenatide twice daily, lixisenatide also showed decreased rates of nausea
Milligan AL, Szabo-Pardi TA, Burton MD
19 In regard to CKD, these clinical trials have also shown positive effects in the composite renal outcomes
