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By Sabina Paglialunga, PhD & Aernout van Haarst, PhD Senior Directors Scientific Affairs Glucagon-Like Peptide-1 (GLP-1) receptor agonists first came to the market in 2005 as a type 2 diabetes mellitus treatment, and they have been making headlines again for their weight reduction effects

ALN-5288 lowers tau levels in preclinical models BioWorld Science Pathological tau accumulation is a key driver of neurodegeneration in Alzheimers disease (AD) and other tauopathies such as progressive supranuclear palsy

A 2019 systematic review evaluating exposure to spironolactone in utero did not find significant evidence of feminization of male individuals

The correlation of symptoms with delayed gastric emptying is variable in diabetic gastropathy, idiopathic gastroparesis, and functional dyspepsia cases