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Proc Natl Acad Sci USA 109:56455650

Its results are significantly lower than GLP-1 medications

Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei

A structured plan for nutrition, activity, and gradual tapering helps support long-term weight maintenance after treatment ends

We want to inform you of an important update regarding Rybelsus (oral semaglutide) and how this may affect your current or future prescription from January 2026 onwards
