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In recent years, regular administration of probiotics, such as Bifidobacterium and Lactobacillus , has also been considered a potential method for preventing IBD (Manzoor et al., 2022), which further indicates the importance of the intestinal flora in IBD (Figure 2

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Research from the STEP trials demonstrated that patients receiving consistent weekly doses experienced sustained weight loss over 68 weeks, with some participants losing 1522% of their body weight

Rather than stopping completely, many patients transition to a lower maintenance dose after reaching their goal weight