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For instance, GLP-1RA have been tested in people with serious mental illness, who could be at a high suicidality risk, showing metabolic benefits with no increase in psychopathology or occurrence of SIS [22]

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FDA Safety Announcement: Ozempic FDA Safety Label Change and Revised Drug LabelThe revised drug label contains a complete list of FDA-approved indications, side effects, warnings, and more

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Historically, the study of the impact of GM on human disease has been focused on the large intestine microbiota because the human colon is the site in the body with the highest abundance of microbes and the most accessible intestinal section