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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

In order to be cost-effective, the net price of tirzepatide (Zepbound) would need to decrease by 30%, while semaglutides (Wegovy) price would have to drop by 82%

In comparison, placebo produced only 3.1% weight loss

Better long-term results: Focusing on body composition rather than weight alone can lead to more sustainable progress, since building muscle helps maintain weight loss and prevent weight regain over time

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