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Whereas DIO control mice showed most consistent changes in KEGG modules associated with reduced bacterial sulfur metabolism, liraglutide and GUB09-145 effects on the gut microbiome were largely associated to effects on bacterial lipid metabolism (increased by liraglutide), sulfur metabolism (increased by both compounds), and Two-component regulatory system (modulated by both compounds)

Semaglutide slows gastric emptying and alters gut motility, which may affect probiotic delivery and efficacy

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July 9, 2018 from Tox & Hound by Dr