generic glp-1 receptor agonists Generic Liraglutide (Victoza) Becomes First
Description
There has been a sharp rise in GLP-1 prescriptions in recent years
10.1016/j.eprac.2023.03.034 15 ChadalavadaP.Simons-LinaresC
Gastrointestinal adverse events: The most common adverse effect is gastrointestinal adverse events
The post hoc analysis of patients only from the PIONEER 6 (evaluating oral semaglutide) and SUSTAIN 6 (evaluating sc semaglutide) studies found a 23.8% reduction in MACEs associated with semaglutide treatment (HR 0.76, 95% CI 0.620.92), especially in the prevention of nonfatal stroke (HR 0.65, 95% CI 0.430.97) [62]
It also promotes hepatic fat oxidation, meaning the liver breaks down stored fat more aggressively
