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Vagal branch ligation and autoradiography Crushing ligation of the four branches (hepatic, celiac, ventral gastric, and dorsal gastric) of the ventral vagal trunk in C57BL/6 J mice was performed with suture thread

However, photoactivation of paraventricular hypothalamic nucleus CRH neurons fails to elicit synaptic activity in arcuate AGRP neurons (Krashes et al., 2014)

HR: 0.56, 95% CI: 0.420.75)

Note that oral semaglutide (Rybelsus) has specific meal-timing requirements that differ from injectable forms, which we'll cover in a later section

Richards P, Pais R, Habib AM, Brighton CA, Yeo GS, Reimann F, Gribble FM